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Cardiovascular malformations in the fetal alcohol syndrome
American Heart Journal
|November 1, 1979
Insights
Fetal alcohol syndrome (FAS) can cause heart defects. This study details cardiac anomalies, including ventricular septal defects and pulmonary artery dysplasia, in two infants with FAS.
Area of Science:
- Pediatric Cardiology
- Developmental Biology
- Teratology
Background:
- Cardiovascular anomalies are common in Fetal Alcohol Syndrome (FAS).
- Cardiac catheterization is rarely performed in infants with FAS.
- Detailed cardiac anomaly descriptions in FAS are scarce.
Observation:
- Two infants diagnosed with Fetal Alcohol Syndrome underwent cardiac catheterization.
- Clinical presentation and diagnostic imaging were analyzed.
Findings:
- Both infants presented with a ventricular septal defect (VSD).
- A rare finding of pulmonary artery dysplasia was observed in both cases.
- The combination of VSD and pulmonary artery dysplasia in FAS is noteworthy.
Implications:
- Highlights the spectrum of cardiovascular malformations in FAS.
- Emphasizes the importance of detailed cardiac evaluation in infants with FAS.
- Contributes to understanding the teratogenic effects of alcohol on cardiac development.
Abstract:
Cardiovascular anomalies are a frequently reported feature of the fetal alcohol syndrome, but only rarely have such children been catheterized. This article fully described the cardiac anomaly in two infants with this syndrome. The malformations found in both cases include a ventricular septal defect, and the rather unusual finding of pulmonary artery dysplasia.