Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

C-reactive protein is a significant predictor of decrease in fat mass in hemodialysis patients.

Yoko Fujino1, Eiji Ishimura, Senji Okuno

  • 1Shirasagi Hospital Kidney Center, Osaka City University Graduate School of Medicine, Osaka, Japan.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|May 18, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential association of fluticasone furoate and budesonide with clinically detected COVID-19: a retrospective cohort study.

BMJ open respiratory research·2026
Same author

Definition of hyperfiltration taking into account age-related decline in renal function in kidney donor candidates with obesity and glucose tolerance disorder.

Hypertension research : official journal of the Japanese Society of Hypertension·2024
Same author

New-onset Kidney Biopsy-proven Membranous Nephropathy Induced End-stage Kidney Disease in a Living Donor.

Internal medicine (Tokyo, Japan)·2024
Same author

Acute Kidney Injury and Remission of Proteinuria in Minimal Change Disease.

Kidney international reports·2022
Same author

Influence of protein intake on the changes in skeletal muscle mass after kidney transplantation.

Clinical nutrition (Edinburgh, Scotland)·2022
Same author

Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study.

Scientific reports·2022

Body fat mass in hemodialysis patients initially increases then decreases, especially in long-term patients. Chronic inflammation, indicated by C-reactive protein (CRP), significantly contributes to this fat mass decline and poorer nutritional status.

Area of Science:

  • Nephrology
  • Clinical Nutrition
  • Biochemistry

Background:

  • Malnutrition and inflammation are prevalent and interconnected issues in patients undergoing hemodialysis.
  • Body fat mass serves as a potential indicator of nutritional status in this patient population.

Purpose of the Study:

  • To analyze annual changes in body fat mass among maintenance hemodialysis patients.
  • To identify factors influencing these body fat mass alterations, particularly in relation to inflammation.

Main Methods:

  • Dual-energy X-ray absorptiometry (DEXA) was used to measure body fat mass in 454 hemodialysis patients at two time points, 12 months apart.
  • Statistical analyses, including correlation and multiple regression, were employed to assess changes and influencing factors.

Related Experiment Videos

Main Results:

  • Patients with less than one year of hemodialysis showed a significant increase in fat mass over 12 months.
  • Patients with over one year of hemodialysis experienced a significant decrease in fat mass.
  • C-reactive protein (CRP) levels were negatively correlated with fat mass changes in long-term patients, indicating inflammation's role.

Conclusions:

  • Body fat mass in hemodialysis patients typically increases initially and then declines, particularly after the first year.
  • Chronic inflammation, evidenced by elevated CRP, is a key factor associated with decreased fat mass and poorer nutritional status in hemodialysis patients.