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Transepidermal water loss dynamics of human vulvar and thigh skin

R Warren1, A Bauer, C Greif

  • 1Winton Hill Technical Center Feminine Care, Procter and Gamble Company, Cincinnati, OH 45224, USA. warren.r@pg.com

Skin Pharmacology and Physiology
|May 18, 2005
PubMed

Refinement in procedures to assess skin surface water loss (SSWL) dynamics of the vulvar skin on a large sample of subjects (60) is described and compared to another semi-occluded skin site, the inner thigh. Vulvar SSWL significantly decreased over a 30-min period from 46.2 +/- 2.6 (SE) to 24.7 +/- 1.6 g m(-2) h (p < 0.001). The inner thigh, another semi-occluded region, showed no similar pattern for SSWL (6.2 +/- 0.3 to 6.6 +/- 0.5 g m(-2) h), and the values were significantly less than those for vulvar skin. There was no significant effect of age, body mass index or atopic status on vulvar SSWL.

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