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Updated: Aug 18, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Recurrent arthralgias in a patient with previous Mayaro fever infection
Shawn F Taylor1, Paresh R Patel, Thomas J S Herold
1Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA. shawnft@aol.com
Abstract:
Mayaro fever is an acute, self-limited, febrile, mosquito-borne viral disease manifested by fever, chills, headache, myalgias, and arthralgias. The virus belongs to the family Togaviridae and the genus Alphavirus. Five other mosquito-borne viruses have been described as causing a similar dengue-like illness. The virus was first isolated in 1954, and the first epidemics were described in 1955 in Brazil and Bolivia. Other cases have been reported in Suriname, Brazil, Peru, French Guiana, and Trinidad. Up to 10 to 15% of febrile illnesses in endemic areas have been attributed to Mayaro virus. The exact pathogenesis and pathophysiology among humans is unknown. Animal models have demonstrated necrosis of skeletal muscle, periosteum, perichondrial tissues, and evidence of meningitis and encephalitis. All previous cases of Mayaro fever describe a self-limited illness. No reports of recurrent symptoms exist in the literature. This report describes a case of recurrent arthralgias in a military service member presenting to the emergency department.
Insights
Mayaro fever, a mosquito-borne illness, typically resolves on its own. This case highlights recurrent joint pain, a previously undocumented symptom, in a military member.
Area of Science:
- Medical Entomology
- Virology
- Infectious Diseases
Background:
- Mayaro virus, an Alphavirus from the Togaviridae family, causes acute febrile illness.
- This mosquito-borne virus is endemic in South America and the Caribbean.
- Mayaro fever presents with symptoms similar to dengue, including fever, headache, myalgias, and arthralgias.
Observation:
- Previously, Mayaro fever has been characterized as a self-limited illness.
- No prior reports documented recurrent symptoms associated with Mayaro virus infection.
- This case report details recurrent arthralgias in a military service member.
Findings:
- The case study focuses on an unusual presentation of Mayaro virus infection.
- Recurrent arthralgias were observed in a military service member presenting to the emergency department.
- This challenges the established understanding of Mayaro fever's self-limiting nature.
Implications:
- The findings suggest a potential for prolonged or recurrent symptoms in Mayaro virus infections.
- Further research is needed to understand the pathogenesis and clinical spectrum of Mayaro fever.
- This case underscores the importance of considering Mayaro virus in febrile illnesses with unusual symptom patterns.
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