Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Herpes zoster ophthalmicus.

M Karbassi1, M B Raizman, J S Schuman

  • 1New England Deaconess Hospital, Department of Surgery, Boston, Massachusetts.

Survey of Ophthalmology
|May 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole-eye transplantation: a look into the past and vision for the future.

Eye (London, England)·2016
Same author

What is a typical optic nerve head?

Experimental eye research·2016
Same author

Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening.

The British journal of ophthalmology·2014
Same author

Outcomes of ab interno trabeculectomy with the trabectome after failed trabeculectomy.

The British journal of ophthalmology·2014
Same author

A method to estimate biomechanics and mechanical properties of optic nerve head tissues from parameters measurable using optical coherence tomography.

IEEE transactions on medical imaging·2014
Same author

Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma.

Eye (London, England)·2014

Herpes zoster ophthalmicus, a reactivation of the chickenpox virus, can cause serious eye complications. Early antiviral treatment is beneficial, but late complications may require steroids or surgery.

Area of Science:

  • Ophthalmology
  • Virology
  • Immunology

Background:

  • Herpes zoster ophthalmicus (HZO) is a reactivation of the varicella-zoster virus (VZV).
  • HZO affects the ophthalmic branch of the trigeminal nerve, leading to ocular complications.
  • While typically seen in healthy adults, HZO is increasingly prevalent in immunocompromised individuals.

Purpose of the Study:

  • To review the pathophysiology, clinical manifestations, and management of herpes zoster ophthalmicus.
  • To discuss the role of antiviral agents and corticosteroids in HZO treatment.
  • To highlight the potential for severe ocular complications and the need for further research.

Main Methods:

  • Literature review of herpes zoster ophthalmicus.
  • Analysis of clinical presentation and diagnostic criteria.

Related Experiment Videos

  • Evaluation of treatment strategies, including antivirals and steroids.

    • Main Results:

    • Early HZO involves corneal dysesthesia and keratopathy, often self-limiting.
    • Smoldering disease can lead to significant ocular pathology via viral invasion, inflammation, and autoimmunity.
    • Antivirals show promise for early symptoms, but their efficacy in preventing late complications requires further study.

    Conclusions:

    • Corticosteroids may be beneficial for acute inflammation in HZO despite risks, pending definitive antiviral treatments.
    • Ocular complications of HZO can be severe and may necessitate surgical intervention.
    • Further research is needed to establish optimal long-term management strategies for HZO.