Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

NONMEMory: a run management tool for NONMEM.

Justin J Wilkins1

  • 1Division of Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa. justin.wilkins@farmbio.uu.se

Computer Methods and Programs in Biomedicine
|May 19, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Covariate modeling in pharmacometrics: General points for consideration.

CPT: pharmacometrics & systems pharmacology·2024
Same author

Semi-mechanistic population pharmacokinetic/pharmacodynamic modeling of a <i>Plasmodium</i> elongation factor 2 inhibitor cabamiquine for prevention and cure of malaria.

Antimicrobial agents and chemotherapy·2023
Same author

Characterization of exposure-response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study.

Cancer chemotherapy and pharmacology·2022
Same author

Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1.

Cancer chemotherapy and pharmacology·2022
Same author

Pharmacometrics in tuberculosis: progress and opportunities.

International journal of antimicrobial agents·2022
Same author

R and nlmixr as a gateway between statistics and pharmacometrics.

CPT: pharmacometrics & systems pharmacology·2021

NONMEMory streamlines pharmacokinetic and pharmacodynamic (PK/PD) data analysis by managing NONMEM projects. This software enhances efficiency, offering project summaries, diagnostic plots, and output management for faster interpretation.

Area of Science:

  • Pharmacometrics
  • Computational Biology
  • Data Science

Background:

  • NONMEM is a powerful tool for nonlinear mixed-effect modeling in PK/PD analysis.
  • Its console-based nature and output format hinder rapid interpretation and efficient project management.
  • Existing tools do not fully address the need for comprehensive project oversight.

Purpose of the Study:

  • To develop and introduce NONMEMory, a project management tool for NONMEM.
  • To enhance the efficiency of PK/PD data analysis by automating trivial tasks.
  • To provide a user-friendly interface for managing NONMEM projects and outputs.

Main Methods:

  • NONMEMory provides a comprehensive overview of NONMEM project runs.
  • Features include detailed summary, comparison, and display of output data.

Related Experiment Videos

  • Includes simple post-run processing and fast diagnostic plots for efficient analysis.

    • Main Results:

    • NONMEMory significantly improves the efficiency of the modeling process.
    • Reduces time spent on non-analytical tasks associated with NONMEM.
    • Facilitates better interpretation and management of PK/PD modeling results.

    Conclusions:

    • NONMEMory is a valuable complementary tool for NONMEM users.
    • It increases efficiency and aids in the interpretation of complex PK/PD models.
    • The software is freely available, promoting wider adoption in the field.