Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Charge-selective recognition at fibroin-modified electrodes for analytical application.

Qiong Cheng1, Tu-Zhi Peng, Xiao-Bo Hu

  • 1Department of Chemistry, Xixi Campus, Zhejiang University, 310028, Hangzhou, P.R. China.

Analytical and Bioanalytical Chemistry
|May 19, 2005
PubMed
Summary

Researchers developed a novel fibroin-modified electrode that changes its charge based on pH. This pH-responsive electrode can attract or repel charged molecules, enabling selective detection of neurochemicals like dopamine.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent advances in early screening and diagnosis of sepsis: a narrative review.

Frontiers in cellular and infection microbiology·2026
Same author

Bioinformatic identification of genes and mechanisms related to acute respiratory distress syndrome and sepsis: A bioinformatic study.

Medicine·2026
Same author

[Auricular thumbtack needle combined with behavioral therapy for female patients with mild to moderate overactive bladder accompanied by anxiety symptoms: a randomized controlled trial].

Zhen ci yan jiu = Acupuncture research·2026
Same author

CitERF25, CitDREB1C, and CitZAT5 orchestrate citrus fruit sugar accumulation via direct and indirect regulation of CitSWEETs.

The Plant journal : for cell and molecular biology·2026
Same author

Satellite Glial Cells in Peripheral Nerve Injury and Regeneration.

Biomedicines·2026
Same author

Synergistic effects of S100 calcium-binding protein A12 combined with Pentraxin 3 in invasive pulmonary aspergillosis and their clinical application prospects.

Frontiers in cellular and infection microbiology·2026

Area of Science:

  • Electrochemistry
  • Biomaterials Science
  • Analytical Chemistry

Background:

  • Silk fibroin membranes possess unique characteristics suitable for analytical applications.
  • Developing selective and responsive electrodes is crucial for advanced chemical sensing.

Purpose of the Study:

  • To report a novel fibroin-modified electrode with pH-responsive charge recognition capabilities.
  • To investigate the electrode's potential for detecting neurocompounds.

Main Methods:

  • Silk fibroin membranes were applied to graphite and carbon-fiber electrodes.
  • The modified electrodes' charge behavior was analyzed across different pH levels.
  • In-vivo determination of dopamine using a fibroin carbon-fiber electrode was performed.

Related Experiment Videos

Main Results:

  • The modified electrode exhibited pH-dependent charge: negative at pH > 4.5 (attracting cations, repelling anions) and positive at pH < 4.5 (attracting anions, repelling cations).
  • The electrode demonstrated pH-responsive charge recognition for neurocompounds.
  • Successful in-vivo determination of cationic neurotransmitter dopamine (DA) concentration was achieved.

Conclusions:

  • The fibroin-modified electrode offers a novel approach to selective ion and molecule detection based on pH.
  • This technology holds promise for in-vivo sensing of neurotransmitters and other charged species.