Related Experiment Video
Updated: Aug 18, 2026

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording
Published on: October 29, 2021
Charge-selective recognition at fibroin-modified electrodes for analytical application
Qiong Cheng1, Tu-Zhi Peng, Xiao-Bo Hu
1Department of Chemistry, Xixi Campus, Zhejiang University, 310028, Hangzhou, P.R. China.
Abstract:
A novel fibroin-modified electrode with charge recognition is reported. The characteristics of silk fibroin membranes have been exploited for analytical applications. The membrane, with an isoelectric point of pH 4.5, was applied to graphite and carbon-fiber electrodes. The modified electrode was negatively charged in solutions of pH > 4.5, and so rejected anions and attracted cations. In solutions of pH < 4.5 the electrode was positively charged, and so rejected cations and attracted anions. The pH-responsive charge recognition of the modified electrode was investigated for some neurocompounds. A fibroin carbon-fiber electrode was used for in-vivo determination of the concentration of the cationic neurotransmitter dopamine (DA).

