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[Case report: cutaneous tuberculosis and tuberculous osteomyelitis]
Aysel Kocagul Celikbaş1, Ayfegül Ulu, Onder Ergönül
1Ankara Numune Egitim ve Araştirma Hastanesi Birinci infeksiyon Hastaliklari ve Klinik Mikrobiyoloji Klinigi, Ankara.
Mikrobiyoloji Bulteni
|May 20, 2005
Summary
Skin and bone tuberculosis (TB) can affect immunocompetent individuals without lung involvement. Early diagnosis and a 12-month treatment regimen led to a successful recovery with no relapse in this case.
Area of Science:
- Infectious Diseases
- Dermatology
- Orthopedics
Background:
- Tuberculosis (TB) is a significant global health concern.
- Extrapulmonary TB, including skin and bone involvement, can be challenging to diagnose.
- Persistent skin lesions warrant consideration of underlying infections like TB, especially in endemic regions.
Observation:
- A 27-year-old immunocompetent male presented with fever, weight loss, and night sweats.
- He developed persistent skin lesions after trauma, unresponsive to antibiotics.
- Imaging revealed osteomyelitis of the tibia, and Mycobacterium tuberculosis was isolated from skin lesions.
Findings:
- The patient was diagnosed with disseminated tuberculosis affecting the skin and bone.
- No pulmonary involvement was detected.
- A 12-month treatment course of isoniazid, rifampin, ethambutol, and morphozinamide was administered, with isoniazid and rifampin continued for the full duration.
Implications:
- This case highlights the importance of considering tuberculosis in the differential diagnosis of persistent skin lesions and osteomyelitis, even in immunocompetent patients.
- Prompt diagnosis and appropriate anti-TB therapy are crucial for successful treatment and preventing relapse.
- Public health awareness regarding extrapulmonary TB manifestations is essential, particularly in TB-endemic countries.