Clinical update on renal aquaporins
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Updated: Aug 18, 2026

Culturing Primary Rat Inner Medullary Collecting Duct Cells
Published on: June 21, 2013
Yung-Chang Chen1, Melissa A Cadnapaphornchai, Robert W Schrier
1Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA.
Abstract:
Following the discovery of the aquaporin-1 water channel over a decade ago, molecular techniques have been developed to examine the role of renal aquaporin water channels under numerous physiological and pathological conditions. The present article reviews current knowledge regarding the function and dysfunction of renal aquaporins in disorders of water metabolism.
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