Preterm birth in Sweden 1973-2001: rate, subgroups, and effect of changing patterns in multiple births, maternal age,

Nils-Halvdan Morken1, Karin Källen, Henrik Hagberg

  • 1Department of Obstetrics and Gynecology, Telemark Hospital, Skien, Norway. nhmorken@online.no

Insights

Sweden

Area of Science:

  • Reproductive Health
  • Public Health Surveillance

Background:

  • Examined trends in preterm birth rates in Sweden from 1973-2001.
  • Described the proportion of spontaneous versus indicated preterm births.
  • Assessed risk factors for preterm birth subgroups.

Purpose of the Study:

  • To evaluate changes in the preterm birth rate in Sweden between 1973 and 2001.
  • To describe the proportion of spontaneous and indicated preterm births.
  • To assess risk factors for preterm birth subgroups from 1991 to 2001.

Main Methods:

  • Population-based register study using the Swedish Medical Birth Register (1973-2001).
  • Subgroup analysis focused on 1991-2001.
  • Calculated odds ratios for risk factors associated with spontaneous and indicated preterm births.

Main Results:

  • Preterm birth rate decreased from 6.3% (1984) to 5.6% (2001).
  • Proportion of multiple births born preterm increased from 0.34% (1973) to 0.71% (2001).
  • Maternal smoking strongly associated with spontaneous preterm birth (<28 weeks gestation); advanced maternal age associated with indicated preterm birth (<28 weeks gestation).

Conclusions:

  • Preterm birth rates in Sweden have declined since the mid-1980s.
  • Subtype composition of preterm births in this low-risk population mirrors that of higher-incidence populations.
Abstract

Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Longitudinal Research02:20

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...