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The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Hepatic resection for breast cancer metastases
A C Okaro1, D J Durkin, G T Layer
1Department of Surgery, Hepatobiliary Unit, The Royal Surrey County Hospital, Guildford, Surrey, UK.
Annals of the Royal College of Surgeons of England
|May 20, 2005
Summary
Hepatic resection for breast cancer liver metastases is a safe procedure with low morbidity and mortality. This study shows a median survival of 31 months following resection in selected patients.
Area of Science:
- Surgical Oncology
- Hepatobiliary Surgery
- Breast Cancer Metastasis
Background:
- Hepatic resection is standard for colorectal cancer metastases.
- Resection of breast cancer liver metastases is debated but effective in select cases.
- This study evaluates outcomes for 8 patients with breast cancer liver metastases.
Purpose of the Study:
- To report the outcomes of hepatic resection in patients with liver metastases from breast cancer.
- To assess the safety and efficacy of liver resection for breast cancer.
- To determine survival rates and complications associated with the procedure.
Main Methods:
- Eight patients with breast cancer liver metastases were considered for hepatic resection (1996-2002).
- Six patients underwent liver resection, including segmentectomy and hemihepatectomy.
- One patient required a repeat hepatectomy after 44 months.
Main Results:
- The resectability rate was 75% with no postoperative deaths or major morbidity.
- Median survival was 31 months post-resection.
- One patient died from recurrence at 6 months; another died disease-free from stroke. Four patients remain alive, one disease-free after repeat resection.
Conclusions:
- Hepatic resection for breast cancer liver metastases is a safe procedure.
- The surgery is associated with low morbidity and mortality rates.
- Selected patients can achieve significant survival benefits.
