Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa
Mark T Albrecht1, Neal L Schiller
1Division of Biomedical Sciences, University of California, Riverside, Riverside, California 92521-0121, USA.
Journal of Bacteriology
|May 20, 2005
Abstract:
To determine whether AlgL's lyase activity is required for alginate production in Pseudomonas aeruginosa, an algLdelta::Gm(r) mutant (FRD-MA7) was created. algL complementation of FRD-MA7 restored alginate production, but algL constructs containing mutations inactivating lyase activity did not, demonstrating that the enzymatic activity of AlgL is required for alginate production.
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