Complications of lumbar puncture in a child treated for leukaemia

Melanie Staebler1, Nadira Azzi, Tayeb Sekhara

  • 1Department of Medical Imaging, Children's University Hospital Queen Fabiola, 15 Avenue JJ Crocq, 1020 Brussels, Belgium.

Pediatric Radiology
|May 20, 2005
PubMed

Insights

Lumbar puncture can cause serious neurological issues like intracranial hypotension and hematomas. Magnetic resonance imaging (MRI) is crucial for diagnosing these post-procedure complications, especially in pediatric leukemia patients.

Area of Science:

  • Neurology
  • Radiology
  • Pediatric Oncology

Background:

  • Lumbar puncture (LP) is a common diagnostic and therapeutic procedure.
  • Neurological complications can arise following lumbar puncture.
  • Early diagnosis and management are essential for favorable outcomes.

Observation:

  • This report details a case of a child undergoing leukemia treatment.
  • The child experienced neurological complications post-lumbar puncture.
  • Magnetic resonance imaging (MRI) was utilized for diagnostic evaluation.

Findings:

  • MRI revealed intracranial hypotension in the patient.
  • Evidence of cervical epidural and cranial/lumbar subdural hematomas was observed.
  • MRI demonstrated the characteristic imaging features of these post-LP complications.

Implications:

  • MRI is the preferred imaging modality for diagnosing neurological complications after lumbar puncture.
  • This case highlights the importance of recognizing and imaging these rare but significant adverse events.
  • Understanding MRI findings aids in timely diagnosis and management of post-LP neurological sequelae in pediatric patients.

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...