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Published on: June 18, 2020
Perinuclear antineutrophil cytoplasmic antibody myeloperoxidase-positive vasculitis in association with ulcerative
Anna D Panani1, Maria Grigoriadou, Eleni Magira
1Critical Care Department, Evangelismos Hospital, Medical School of Athens University, Ipsilantou 45-47, Athens, 10676, Greece. apanani@med.uoa.gr
Abstract:
We describe a patient with ulcerative colitis (UC) who developed small vessel vasculitis. Perinuclear antineutrophil cytoplasmic antibody myeloperoxidase (p-ANCA-MPO) positivity was detected along with a highly elevated titer of anticardiolipin antibodies. A total proctocolectomy was undertaken and the patient, more than 5 years later, remains in very good condition. The possible causative association between the UC, the p-ANCA-MPO-positive small vessel vasculitis, and the anticardiolipin antibodies is discussed.
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