Related Experiment Video

Updated: Aug 17, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Effects of giant left atrium on thromboembolism after mitral valve replacement

Veysel Kutay1, Kaan Kirali, Hasan Ekim

  • 1Cardiovascular Surgery Department, Van Yuksek Ihtisas Hospital, Van, Turkey. vkutay@yahoo.com

Asian Cardiovascular & Thoracic Annals
|May 21, 2005
PubMed

Insights

This study found that patients with giant left atrium undergoing mitral valve replacement experienced no increased risk of thromboembolic events. Giant left atrium size significantly decreased post-surgery, showing positive outcomes.

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Thromboembolic Disease

Background:

  • Giant left atrium is a complex condition often associated with mitral valve disease.
  • The risk of thromboembolic events in these patients post-mitral valve replacement requires careful evaluation.

Purpose of the Study:

  • To assess the incidence of thromboembolic events in patients with giant left atrium ( > 6.5 cm) following mitral valve replacement.
  • To evaluate the impact of mitral valve replacement on left atrium size and associated clinical outcomes.

Main Methods:

  • A retrospective study of 126 patients undergoing mitral valve replacement between January 2000 and September 2002.
  • Patients were divided into two groups: Group A (giant left atrium, n=34) and Group B (normal left atrium, n=92).
  • Preoperative and postoperative data, including thromboembolic events, thrombosis, hemorrhage, and hemodynamic parameters, were analyzed.

Main Results:

  • Preoperative atrial fibrillation was significantly higher in Group A (85.2%) compared to Group B (61.9%).
  • Mitral valve replacement significantly reduced left atrium mean diameter in Group A (8.1 cm to 6.2 cm).
  • No significant differences in thrombosis, hemorrhage, or thromboembolism rates were observed between the groups.

Conclusions:

  • Mitral valve replacement in patients with giant left atrium leads to a significant reduction in left atrium size.
  • Patients with giant left atrium demonstrate positive clinical and hemodynamic responses post-mitral valve replacement.
  • No direct relationship was evident between giant left atrium and increased thromboembolic events during follow-up.

More Related Videos

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...