Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breast sentinel lymph node navigation with three-dimensional interstitial multidetector-row computed tomographic

Kazuyoshi Suga1, Shigeru Yamamoto, Akira Tangoku

  • 1Department of Radiology, Yamaguchi University School of Medicine, Japan. sugar@po.cc.yamaguchi-u.ac.jp

Investigative Radiology
|May 21, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multicenter prospective study of dedicated breast positron emission tomography (dbPET) for breast cancer: examination in preoperative patients.

BMC medical imaging·2026
Same author

Prognostic Markers for Major Adverse Cardiovascular Events in Patients With Cardiac Sarcoidosis Following Steroid Therapy.

JACC. Cardiovascular imaging·2025
Same author

Practice guidelines on endoscopic surgery for qualified surgeons by the endoscopic surgical skill qualification system: Breast.

Asian journal of endoscopic surgery·2024
Same author

Diagnostic Utility of Specific Frailty Questionnaire: The Kihon Checklist for Hippocampal Atrophy in COPD.

Journal of clinical medicine·2024
Same author

Correlation between frailty and reduction in cortical thickness in patients with chronic obstructive pulmonary disease.

Scientific reports·2024
Same author

Long-Term Outcomes of S-1 Combined With Low-Dose Docetaxel as Neoadjuvant Chemotherapy (N-1 Study, Phase II Trial) in Patients With Operable Breast Cancer.

Clinical breast cancer·2024

Three-dimensional multidetector-row computed tomographic lymphography (3D MDCT-LG) accurately navigated breast sentinel lymph node biopsies in all patients. This technique offers high sensitivity and accuracy for identifying breast cancer spread, improving surgical planning.

Area of Science:

  • Radiology
  • Oncology
  • Surgical Navigation

Background:

  • Sentinel lymph node biopsy (SLN) is crucial for staging breast cancer.
  • Accurate SLN identification is essential to avoid unnecessary axillary dissection.
  • Current methods for SLN localization can have limitations.

Purpose of the Study:

  • To evaluate the utility of three-dimensional multidetector-row computed tomographic lymphography (3D MDCT-LG) for navigating breast SLN biopsy.
  • To assess the accuracy and reliability of 3D MDCT-LG in identifying SLNs in early-stage breast cancer patients.

Main Methods:

  • 68 early-stage breast cancer patients underwent 3D MDCT-LG using interstitial iopamidol injection.
  • Lymphatic drainage patterns and SLN anatomy were visualized.

Related Experiment Videos

  • SLN biopsy was performed under 3D MDCT-LG navigation, followed by axillary lymph node dissection for accuracy assessment.

    • Main Results:

    • 3D MDCT-LG clearly visualized SLNs and their afferent lymphatic vessels in all patients.
    • SLNs were accurately located in 100% of cases under 3D MDCT-LG guidance.
    • The sensitivity, false-negative rate, and accuracy of the 3D MDCT-LG-navigated SLN biopsy were 92%, 7%, and 98%, respectively.

    Conclusions:

    • Topographic 3D interstitial MDCT-LG is a reliable navigator for breast SLN biopsy.
    • This technique provides detailed anatomical information for precise SLN identification.
    • 3D MDCT-LG offers a widely available and effective tool for improving SLN biopsy procedures.