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Related Experiment Videos

Multishot diffusion-weighted imaging features in spinal cord infarction.

Jinsong Zhang1, Yi Huan, Yunqiu Qian

  • 1Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR China. zhangjs@tom.com

Journal of Spinal Disorders & Techniques
|May 21, 2005
PubMed
Summary
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Diffusion-weighted imaging (DWI) effectively detects spinal cord infarction, offering better contrast than T2-weighted images. This technique aids in assessing ischemic changes and differentiating diagnoses, especially in subacute stages.

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Spinal cord infarction is a rare but devastating condition.
  • Accurate and timely diagnosis is crucial for patient outcomes.
  • Distinguishing infarction from inflammatory diseases and tumors can be challenging.

Purpose of the Study:

  • To evaluate the utility of multishot, navigator-corrected, echo-planar (EP) diffusion-weighted imaging (DWI) for clinical spinal cord imaging.
  • To analyze DWI findings in patients with ischemic spinal cord lesions.
  • To assess the value of DWI in differentiating spinal cord infarction from other pathologies like inflammation and tumors.

Main Methods:

  • Six patients with suspected spinal cord ischemia underwent DWI using a multishot, navigator-corrected, EP pulse sequence on a 1.5 T MR system.

Related Experiment Videos

  • Apparent diffusion coefficient (ADC) values were calculated.
  • Contrast-enhanced MRI and FLAIR sequences were also performed in some patients.

    • Main Results:

    • DWI revealed abnormalities in all six patients, with better signal contrast compared to T2-weighted images.
    • Lesion ADC values (0.23-0.47 x 10(-3) mm2/s) were significantly lower than normal spinal cord (0.89 x 10(-3) mm2/s).
    • Contrast-enhanced MRI showed minimal enhancement in most lesions, while FLAIR images had poor contrast.

    Conclusions:

    • MRI, particularly DWI, is valuable for detecting spinal cord infarction.
    • Multishot DWI provides crucial information for assessing ischemic changes and aids in differential diagnosis of spinal cord lesions.