Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A non-fatal oleander poisoning.

J Pietsch1, R Oertel, S Trautmann

  • 1Institute of Legal Medicine, Medical Faculty Carl Gustav Carus, Dresden Technical University, Fetscherstr. 74, 01307, Dresden, Germany. Joerg.Pietsch@mailbox.tu-dresden.de

International Journal of Legal Medicine
|May 21, 2005
PubMed
Summary

This case study highlights oleander poisoning, emphasizing the need for accurate toxicological analysis. A serum oleandrin level of 1.6 ng/ml was confirmed, suggesting a toxic range of 1.0-2.0 ng/ml.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Executive anosognosia in progressive supranuclear palsy versus Parkinson's disease.

Frontiers in neurology·2026
Same author

Snapshot of the <i>Seconds</i>-Pellicle: Ultrastructure and Proteomic Changes.

Journal of dental research·2025
Same author

Age prediction of hematoma using hyperspectral imaging (HSI).

Forensic science, medicine, and pathology·2025
Same author

Detection of tooth-colored composite restorations via optical analysis - hyperspectral imaging (400 nm-1000 nm) and near-infrared spectroscopy (1550 nm-1950 nm).

Forensic science international·2025
Same author

Contactless in vitro detection of carboxyhemoglobin using hyperspectral imaging (HSI).

Forensic science, medicine, and pathology·2025
Same author

Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation.

Acta neuropathologica communications·2024

Area of Science:

  • Clinical Toxicology
  • Pharmacology
  • Cardiology

Background:

  • Oleander (Nerium oleander) ingestion can cause severe cardiac toxicity due to cardiac glycosides like oleandrin.
  • Accurate and timely toxicological analysis is crucial for managing poisoning emergencies.
  • Cardiac symptoms in poisoning cases necessitate prompt diagnostic evaluation.

Observation:

  • A 47-year-old female presented with cardiac symptoms 18 hours after ingesting oleander blooms.
  • Initial immunochemical assays for digitoxin-related compounds were non-specific.
  • High-performance liquid chromatography/tandem mass spectrometry (HPLC/MS/MS) confirmed oleandrin at 1.6 ng/ml.

Findings:

  • HPLC/MS/MS analysis is essential for specific identification and quantification of oleandrin in suspected oleander poisoning.

Related Experiment Videos

  • The study proposes a toxic serum concentration range for oleandrin between 1.0 and 2.0 ng/ml.
  • Non-specific immunoassays may lead to over-interpretation in clinical toxicology.

    • Implications:

    • Accurate toxicological testing aids in appropriate clinical management and treatment of oleander poisoning.
    • Establishing specific concentration thresholds improves diagnostic accuracy for oleander-induced cardiotoxicity.
    • This case underscores the importance of specialized toxicological services in emergency medicine.