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Updated: Aug 17, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Image-guided endoscopic transsphenoidal removal of pituitary adenoma]
Qui-Hang Zhang1, Hai-Sheng Liu, Da-Zhang Yang
1Department of Otorhinolaryngology, Xuanwu Hospital, Affiliated to Capital University of Medical Sciences, Beijing 100053, China. zhangqiuhang@yahoo.com.cn
Objective:
To assess the role of neuronavigation in assisting endoscopic transsphenoidal surgery for pituitary adenomas.
Methods:
Ten endoscopic endonasal transsphenoidal reoperations for pituitary adenomas were selected. Clinical records were reviewed retrospectively. Five of 10 patients had gigantic adenoma, 3 microadenoma, 2 large adenoma.
Results:
The mean setup time was 5 minutes, and the operative time was 50 minutes in image-guided procedures. In all cases, the system worked well without malfunction. Continuous information regarding instrument location and trajectory was provided to the surgeon. Measurements of intraoperative accuracy in the axial, coronal, and.sagittal planes indicated a mean verified system error of 1.5 mm. for pituitary adenomas. After operation, the symptoms relieved in all patients.
Conclusions:
Neuronavigation can be applied during endonasal transsphenoidal endoscopic surgery and requires a minimal amount of time. It makes reoperation easier, faster, and safer.
