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Updated: Aug 17, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
[CT findings in patients with chronic thrombembolic pulmonary hypertension]
Marc Heinrich1, Aleksandar Grgic, Dietmar Tscholl
1Radiologische Klinik, Abteilung für Radiodiagnostik, Universitätsklinikum des Saarlandes, Homburg. ramhei@uniklinik-saarland.de
Insights
Chronic thromboembolic pulmonary hypertension (CTEPH) is more common than previously thought. Early diagnosis via CT imaging is crucial for curative treatment with pulmonary thromboendarterectomy (PTE).
Area of Science:
- Cardiology
- Radiology
- Pulmonology
Background:
- Chronic thromboembolic pulmonary hypertension (CTEPH) is an underdiagnosed condition following pulmonary embolism.
- Untreated CTEPH carries a high mortality rate.
- Pulmonary thromboendarterectomy (PTE) offers a potential cure, necessitating early and accurate diagnosis.
Purpose of the Study:
- To review CT findings in CTEPH patients.
- To differentiate CTEPH from other pulmonary hypertension causes using CT.
- To correlate CT imaging features with PTE surgical outcomes.
Main Methods:
- Review of CT imaging in CTEPH diagnosis and operability assessment.
- Comparison of CT findings with acute pulmonary embolism and primary pulmonary hypertension.
- Analysis of CT features predicting surgical success post-PTE.
Main Results:
- Multidetector CT is a key diagnostic tool for CTEPH, aiding in diagnosis and operability assessment.
- CT effectively differentiates CTEPH from other pulmonary hypertension conditions.
- Specific CT imaging features correlate with surgical outcomes after PTE.
Conclusions:
- CT plays a vital role in the early diagnosis and management of CTEPH.
- Accurate CT interpretation is essential for patient selection and predicting outcomes of PTE.
- Correlating CT findings with pulmonary hypertension severity guides treatment decisions.
Abstract:
Chronic thromboembolic pulmonary hypertension (CTEPH) is thought to be a rare complication of pulmonary embolism. However, it was recently demonstrated that CTEPH is more common than previously thought after pulmonary embolism. Without treatment, CTEPH is associated with a very high mortality rate. Making the correct diagnosis early is essential, because there is a potential curative treatment in the form of pulmonary thromboendarterectomy (PTE). Because of the unspecific clinical symptoms of CTEPH, the different imaging modalities play a crucial role in diagnosis making. Since the introduction of the multidetector CT technology, CT has become an important part in the diagnostic work up of pulmonary embolism and CTEPH and is often used as a first-line diagnostic tool. CT is not only a reliable tool for the diagnosis of CTEPH, but also is helpful in estimating the operability of these patients. PTE is still associated with a mortality rate of about 10%. Particularly an insufficient decrease of the pulmonary vascular resistance after PTE leads to a very high mortality rate. Therefore, it is crucial to correlate the degree of the surgical accessible obstruction of the pulmonary vasculature with the degree of pulmonary hypertension in deciding for or against PTE. The aim of this review is to describe the CT findings in patients with CTEPH and their use in differentiating CTEPH from other diseases like acute pulmonary embolism and primary pulmonary hypertension. Moreover, the correlation of different CT imaging features with surgical success after PTE will be discussed.
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