Related Experiment Video
Updated: Aug 17, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Cutaneous metastasis of a renal carcinoma: case report and review]
Alfonso Barbagelata López1, Manuel Ruibal Moldes, Antonio Blanco Díez
1Servicio de Urología, Hospital Juan Canalejo, La Coruña, España. Barbagelata@telefonica.net
Objectives:
To report another rare case of skin metastasis from a renal adenocarcinoma, analyzing the prognostic significance, response to therapy, and clinical presentation after a bibliographic review.
Methods/Results:
We report the case of a 65-year-old male with a cutaneous metastasis in the root of his inferior left extremity one year after right nephrectomy for a clear cell adenocarcinoma.
Conclusions:
Skin metastases usually present as solitary cutaneous lesions of variable macroscopic features and rapid growing; the diagnosis is made by histological analysis, being excision the treatment of choice whenever possible. Prognosis is better for solitary lesions appearing asynchronously with the primary tumor, and among them the longer the time after diagnosis of initial lesion they appear the better the prognosis.
