Related Experiment Video

Updated: Aug 17, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

US with contrast medium in the diagnosis of abdominal Castleman's disease

Gennaro Annunziata1, Pasquale Martino, Silvano Palazzo

  • 1Dipartimento dell'Emergenza e dei Trapianti di Organi, Università di Bari, Italy.

Archivio Italiano Di Urologia, Andrologia : Organo Ufficiale [Di] Societa Italiana Di Ecografia Urologica E Nefrologica
|May 24, 2005
PubMed

Insights

Castleman's disease is a rare lymphoproliferative disorder. This review highlights imaging findings, suggesting ultrasound contrast media could aid diagnosis of abdominal Castleman's disease, potentially reducing reliance on CT and MRI.

Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Castleman's disease is a rare, heterogeneous lymphoproliferative disorder with uncertain etiology.
  • Abdominal Castleman's disease is uncommon, with retroperitoneal, mesenteric, and pelvic sites reported.
  • Diagnosis is often incidental, identified through imaging modalities like ultrasound (US), CT, and MRI.

Observation:

  • Imaging characteristics of abdominal Castleman's disease were reviewed across 31 cases.
  • Contrast enhancement patterns on CT and MRI varied based on lymph node size: homogeneous for <5 cm and dyshomogeneous for >5 cm.
  • The current case demonstrated similar vascular enhancement behavior on US, CT, and MRI after contrast administration.

Findings:

  • Abdominal Castleman's disease presents with diverse imaging findings.
  • Specific contrast enhancement patterns on CT/MRI correlate with lymph node size.
  • Ultrasound showed comparable vascular enhancement to CT/MRI in the observed case.

Implications:

  • Further research into ultrasound contrast media is warranted for diagnosing abdominal Castleman's disease.
  • Successful validation could reduce the need for CT and MRI in evaluating localized abdominal masses.
  • This may lead to safer, more accessible diagnostic approaches for Castleman's disease.

More Related Videos

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...