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Fentanyl.

Theodore H Stanley¹

¹University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.

Journal of Pain and Symptom Management

|May 24, 2005

Summary

This summary is machine-generated.

Fentanyl remains the top perioperative opioid globally, despite newer alternatives. Its versatility and effectiveness ensure its continued use by anesthesiologists and pain physicians worldwide.

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Area of Science:

Anesthesiology and Pain Management
Pharmacology

Background:

Fentanyl, a potent synthetic opioid, was first synthesized over 40 years ago.
It is widely recognized for its lipid solubility and potent analgesic properties.

Observation:

Fentanyl is the most frequently utilized opioid in the perioperative setting globally.
Its application has expanded to various acute and chronic pain conditions over the past two decades.
Numerous novel drug delivery systems for fentanyl have been developed.

Findings:

Despite the emergence of alternative opioids with improved potency, safety profiles, and varied onset/duration characteristics, fentanyl maintains its primary role.
Anesthesiologists and Certified Registered Nurse Anesthetists consistently rely on fentanyl for perioperative pain management.

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Pain physicians globally continue to favor fentanyl for managing diverse pain conditions.

Implications:

Fentanyl's established efficacy and adaptability solidify its position as a cornerstone in perioperative care.
The ongoing development of delivery systems suggests a sustained focus on optimizing fentanyl's therapeutic utility.
Understanding fentanyl's enduring role is crucial for pain management strategies and pharmaceutical research.