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Updated: Aug 17, 2026

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
Published on: November 25, 2017
A novel phosphatidylinositol manno-oligosaccharide (dPIM-8) from Gordonia sputi
Richard H Furneaux1, Clas L Landersjö, Jackie L McCullough
1Industrial Research Limited, PO Box 31-310, Lower Hutt, New Zealand.
Abstract:
The deacylated phosphatidylinositol manno-oligosaccharides (dPIMs) from the glycosyl phosphatidylinositol (GPI) carbohydrate antigen anchor of Gordonia sputi were the known 2,6-di-O-alpha-mannopyranosyl-myo-inositol glycerophosphate (dPIM-2) and the illustrated novel compound (dPIM-8), which could not be separated from dPIM-7 and dPIM-6, these three compounds being present in the mixture in the molar ratios 1.0:0.65:0.4. dPIM-8 is an analogue of dPIM-2 (and also of dPIM-7 and dPIM-6) in having alpha-mannopyranose and an alpha-mannopyranosyl linked heptasaccharide bonded to O-2 and O-6, respectively, of the inositol. The dPIM-8 species has not been found previously. [structure: see text]
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