Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Imaging of patellar cartilage with a 2D multiple-echo data image combination sequence.

Marius R Schmid1, Christian W A Pfirrmann, Peter Koch

  • 1Department of Radiology, University Hospital Balgrist, Forchstrasse 340, Zurich CH-8008, Switzerland.

AJR. American Journal of Roentgenology
|May 24, 2005
PubMed
Summary

The 2D multiple-echo data image combination (MEDIC) MRI sequence effectively detects patellar cartilage defects, showing high accuracy and specificity for low- to intermediate-grade lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Value of multiparametric MRI as a potential marker to differentiate membranous nephropathy from IgA nephropathy.

BMC medical imaging·2026
Same author

A Study on Predicting Split Renal Function Using Renal Blood Flow Weighted Estimated Glomerular Filtration Rate From Arterial Spin Labeling MRI.

Journal of magnetic resonance imaging : JMRI·2026
Same author

Where i got to - in radiology.

Current problems in diagnostic radiology·2026
Same author

Noninvasive Differentiation of Indolent from Aggressive Renal Neoplasms with MR Fingerprinting Combined with Diffusion/Perfusion MRI.

Radiology·2026
Same author

MARS MRI for the Diagnosis of Aseptic Stem Loosening in Cementless Total Hip Arthroplasty.

Investigative radiology·2026
Same author

Nomograms with arterial spin labeling for diagnosing early-stage chronic kidney disease.

International urology and nephrology·2025

Area of Science:

  • Orthopedic imaging
  • Radiology
  • Biomedical engineering

Background:

  • Patellar cartilage defects are common and can lead to pain and dysfunction.
  • Accurate detection of these defects is crucial for effective treatment planning.
  • Existing MRI sequences have limitations in visualizing subtle cartilage changes.

Purpose of the Study:

  • To evaluate the diagnostic performance of the 2D multiple-echo data image combination (MEDIC) MRI sequence.
  • To assess its ability to detect patellar cartilage defects compared to surgical grading.
  • To determine the sensitivity, specificity, and accuracy of the 2D MEDIC sequence.

Main Methods:

  • 52 patients undergoing knee surgery had pre-operative MRIs including an axial 2D MEDIC sequence.
  • Patellar cartilage was graded surgically (0-4) and via MRI.

Related Experiment Videos

  • Two blinded reviewers analyzed cartilage using the 2D MEDIC sequence.
  • Sensitivity, specificity, accuracy, and interobserver agreement were calculated.

    • Main Results:

    • The 2D MEDIC sequence achieved high diagnostic performance for detecting patellar cartilage defects.
    • With a threshold of grade 2 or higher, sensitivity was 79%, specificity 82%, and accuracy 81%.
    • Increasing the threshold to grade 3 or higher improved performance to 83% sensitivity, 91% specificity, and 90% accuracy.
    • Good interobserver agreement was observed (weighted kappa = 0.68).

    Conclusions:

    • The 2D MEDIC sequence demonstrates significant diagnostic value for patellar cartilage defects.
    • Its performance is comparable to other advanced cartilage imaging sequences.
    • The sequence offers high sensitivity and excellent specificity for low- to intermediate-grade defects.