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Updated: Aug 17, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Optimization of gadodiamide concentration for MR arthrography at 3 T
Jeffrey N Masi1, David Newitt, Christian A Sell
1Department of Radiology, University of California, San Francisco, 400 Parnassus Ave., A 367, Box 0628, San Francisco, CA 94143-0628, USA.
Objective:
The purpose of our study was to determine the optimal concentration of a gadolinium-based contrast agent (gadodiamide) for direct MR arthrography at 3 T compared with 1.5 T in an in vitro study.
Conclusion:
Optimized concentrations of gadolinium-based contrast agents for MR arthrography are similar at 3 and 1.5 T, although a slightly greater dilution may be useful at 3 T. Signal-to-noise ratio peak levels are significantly reduced by adding an iodinated contrast agent, relatively significantly more at 3 T than at 1.5 T.
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