Jove
Visualize
Contact Us

Related Experiment Videos

Audiological profile in Apert syndrome.

D Rajenderkumar1, D-E Bamiou, T Sirimanna

  • 1Department of Audiological Medicine, Great Ormond Street Children's Hospital, Great Ormond Street, London, UK. deepakrkumar@hotmail.com

Archives of Disease in Childhood
|May 24, 2005
PubMed
Summary

Apert syndrome often causes persistent middle ear fluid and permanent conductive hearing loss in most patients by age 20. This study clarifies the high incidence of hearing impairment in Apert syndrome.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The audiovestibular profile of Brown-Vialetto-Van Laere syndrome.

The Journal of laryngology and otology·2021
Same author

A randomised controlled study of mindfulness meditation versus relaxation therapy in the management of tinnitus.

The Journal of laryngology and otology·2017
Same author

Mining balance disorders' data for the development of diagnostic decision support systems.

Computers in biology and medicine·2016
Same author

Dehiscence of the posterior and superior semicircular canal presenting in pregnancy.

B-ENT·2013
Same author

Effects of chronic noise exposure on speech-in-noise perception in the presence of normal audiometry.

The Journal of laryngology and otology·2013
Same author

Assessment of traffic Noise and its impact on certain personnel.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2012
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Genetics and Syndromes
  • Otolaryngology
  • Pediatric Health

Background:

  • Apert syndrome is a craniosynostosis disorder.
  • Conductive hearing loss is frequently reported in Apert syndrome patients.
  • The exact cause of hearing loss in Apert syndrome remains debated.

Purpose of the Study:

  • To investigate the incidence and causes of hearing impairment in Apert syndrome.
  • To analyze the long-term progression of hearing issues in these patients.

Main Methods:

  • Retrospective analysis of case notes from 1970 to 2003.
  • Inclusion of patients diagnosed with Apert syndrome.
  • Data extraction on hearing impairment and otitis media.

Main Results:

  • Seventy Apert syndrome patient case notes were analyzed.
  • Congenital hearing impairment occurred in 3-6% of patients.
  • Over 56% developed permanent conductive hearing loss by age 10-20.
  • Nearly all patients experienced persistent otitis media with effusion.

Conclusions:

  • Otitis media with effusion is a primary factor in conductive hearing loss in Apert syndrome.
  • Persistent middle ear issues contribute to long-term hearing deficits.
  • Early and continuous otological monitoring is crucial for Apert syndrome patients.

Related Experiment Videos