Palliation of heart failure

Mellar P Davis1, Nancy M Albert, James B Young

  • 1The Harry R Horvitz Center for Palliative Medicine, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, USA.

Insights

Stage D heart failure significantly impacts morbidity and mortality, often exceeding that of many cancers. Palliative care and cardiology collaboration are essential for managing these severe heart failure symptoms.

Area of Science:

  • Cardiology
  • Palliative Care
  • Heart Failure Pathophysiology

Background:

  • Heart failure is a leading cause of death and illness in the US.
  • Stage D heart failure presents severe symptoms and high mortality rates, comparable to advanced cancers.
  • Understanding heart failure pathophysiology has evolved, revealing links to ventricular remodeling and neurohumoral responses.

Purpose of the Study:

  • To highlight the critical need for palliative care in advanced heart failure (Stage D).
  • To emphasize the importance of interdisciplinary collaboration between cardiology and palliative care specialists.
  • To underscore the necessity of palliative strategies for highly symptomatic Stage D heart failure patients.

Main Methods:

  • Review of current understanding of Stage D heart failure pathophysiology.
  • Analysis of evolving drug classes targeting ventricular remodeling and neurohumoral responses.
  • Discussion on the role of palliative care in conjunction with existing therapies.

Main Results:

  • Despite advancements in drug and device therapies, Stage D heart failure management still requires palliative interventions.
  • Collaboration between cardiology and palliative care specialists can improve symptom management.
  • Interdisciplinary approaches form the foundation for effective research in advanced heart failure.

Conclusions:

  • Stage D heart failure demands integrated palliative care strategies.
  • Enhanced collaboration between cardiology and palliative care is crucial for improving patient outcomes.
  • Further research is needed to optimize palliative care in advanced heart failure.

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