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Updated: Aug 17, 2026

High-throughput Purification of Affinity-tagged Recombinant Proteins
Published on: August 26, 2012
[Study of the novel tissue-specific RNA polymerase II transcription factor]
Abstract:
It has been established that retrogenes lose introns and regulatory regions. Most of them become pseudogenes, but some acquire tissue-specific functions. In this study, a contrary situation is described, when a retrogene from Drosophila melanogaster performs the main functions and is expressed in all tissues, while the initial gene is active only in a small part of the male germ cells. It is suggested that this phenomenon resulted from retroposition of the initial precursor gene in the transcription-suitable region of the genome.
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