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Updated: Aug 17, 2026

Enhanced Photoluminescence of Curcuma longa Extracts via Chitosan-Mediated Energy Transfer for Textile Authentication Applications
Published on: December 22, 2023
Synthesis and biological evaluation of aromatic enones related to curcumin
Thomas Philip Robinson1, Richard B Hubbard, Tedman J Ehlers
1Center for Biomolecular Structure and Dynamics, Department of Chemistry, University of Georgia, Athens, GA 30602, USA.
Abstract:
Curcumin, a natural product isolated from the spice turmeric, has been shown to exhibit a wide range of pharmacological activities including certain anti-cancer properties. It has been specifically shown to be an effective inhibitor of angiogenesis both in vitro and in vivo. Using curcumin as a lead compound for anti-angiogenic analog design, a series of structurally related compounds utilizing a substituted chalcone backbone have been synthesized and tested via an established SVR cell proliferation assay. The results have yielded a wide range of compounds that equal or exceed curcumin's ability to inhibit endothelial cell growth in vitro. Due to both their commercial availability and their fairly straightforward synthetic preparation, these low molecular weight compounds are attractive leads for developing future angiogenic inhibitors.
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