Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subacute inflammatory demyelinating polyneuropathy in children.

M Victoria Rodriguez-Casero1, Lloyd K Shield, Andrew J Kornberg

  • 1Department of Neurology, Royal Children's Hospital, Parkville, Victoria, Australia.

Neurology
|May 25, 2005
PubMed
Summary

This study describes five children with subacute demyelinating polyneuropathy, a condition characterized by motor weakness and nerve damage. Fortunately, these children experienced a full recovery after corticosteroid treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sleep and Fatigue in Children and Adolescents With Multiple Sclerosis.

Journal of child neurology·2025
Same author

Neuroblastic Tumor Causing Toe-Walking Without Mechanical Compression of the Spinal Cord or Nerve Roots.

Pediatric neurology·2025
Same author

A contemporary analysis of the Australian clinical and genetic landscape of spinal muscular atrophy: a registry based study.

The Lancet regional health. Western Pacific·2024
Same author

Genome and RNA sequencing boost neuromuscular diagnoses to 62% from 34% with exome sequencing alone.

Annals of clinical and translational neurology·2024
Same author

Pilot study of a virtual weight management program for Duchenne muscular dystrophy.

Muscle & nerve·2024
Same author

Multiple cranial neuropathies in an adolescent with myelin-oligodendrocyte glycoprotein antibody-associated disease.

Journal of paediatrics and child health·2023

Area of Science:

  • Pediatric Neurology
  • Neuroimmunology
  • Clinical Neuroscience

Background:

  • Subacute demyelinating polyneuropathy (SDPN) is a rare neurological disorder affecting peripheral nerves.
  • Understanding the clinical spectrum and prognosis of SDPN in children is crucial for effective management.

Observation:

  • Five pediatric cases of subacute demyelinating polyneuropathy were analyzed.
  • Patients presented with a monophasic illness over 4-8 weeks, primarily motor deficits, and areflexia.
  • Cranial nerve, autonomic, and respiratory systems were largely unaffected.

Findings:

  • Cerebrospinal fluid (CSF) showed elevated protein levels.
  • Electrophysiology confirmed demyelination of peripheral nerves.
  • All patients demonstrated a positive response to corticosteroid therapy.

Related Experiment Videos

Implications:

  • Subacute demyelinating polyneuropathy in children typically follows a benign course.
  • Prompt diagnosis and corticosteroid treatment can lead to complete recovery.
  • This suggests an immune-mediated etiology responsive to immunosuppression.