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Updated: Aug 17, 2026

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Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
Published on: April 25, 2014
Nested polymerase chain reaction for assessing the clinical course of tuberculous meningitis
T Takahashi1, T Nakayama, M Tamura
1Division of Neurology, Advanced Medical Research Center, Nihon University School of Medicine, Tokyo, Japan.
Neurology
|May 25, 2005
Abstract:
The authors examined the usefulness of nested PCR (N-PCR) to detect Mycobacterium tuberculosis (MTB) DNA in CSF for assessing the clinical course of tuberculous meningitis (TBM). N-PCR successfully detected MTB DNA in all nine CSF samples from patients with suspected TBM. During anti-tuberculosis treatments, N-PCR results converted from positive to negative, correlating with the improvement of the patient's clinical condition.

