Gastrointestinal complications of fundoplication
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Updated: Aug 17, 2026

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Published on: September 22, 2023
1Department of Gastroenterology, Hepatology and Nutrition, Royal Children's Hospital, Herston Road, Herston, Brisbane, QLD 4029, Australia. flconnor@tpgi.com.au
Insights
Fundoplication surgery is effective for children with severe acid reflux. However, some patients experience gastrointestinal issues post-surgery, requiring further investigation for proper management.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Digestive Health
Background:
- Medically refractory gastroesophageal reflux disease (GERD) in children often necessitates surgical intervention.
- Fundoplication is a common surgical procedure for managing GERD in pediatric patients.
- While generally safe and effective, a subset of patients develop postoperative gastrointestinal (GI) dysfunction.
Purpose of the Study:
- To outline the spectrum of postoperative gastrointestinal dysfunctions following fundoplication in children.
- To identify potential causes and diagnostic approaches for these complications.
- To guide clinical management strategies for pediatric patients experiencing post-fundoplication GI issues.
Main Methods:
- Review of clinical presentations and outcomes in pediatric patients undergoing fundoplication.
- Analysis of diagnostic investigations including pHmetry, videofluoroscopy, endoscopy, and motility studies.
- Evaluation of dumping provocation testing for suspected rapid gastric emptying.
Main Results:
- Postoperative symptoms can include chest pain, dysphagia (5%), gas bloat (2-4%), diarrhea (up to 20%), and dumping syndrome (up to 30%).
- These symptoms may stem from recurrent GERD, surgical complications (e.g., wrap disruption), functional disturbances (e.g., rapid gastric emptying), or alternative diagnoses.
- Diagnostic workup is crucial for differentiating causes and guiding treatment.
Conclusions:
- Fundoplication is a viable treatment for refractory GERD in children, but vigilance for postoperative GI dysfunction is essential.
- A systematic and detailed investigation is required to determine the underlying cause of persistent or new-onset GI symptoms.
- Accurate diagnosis is key to effective management and improving patient outcomes after pediatric fundoplication.
Abstract:
In children with medically refractory gastroesophageal reflux disease (GERD), fundoplication is effective and safe. However, in a subset of patients, gastrointestinal dysfunction occurs postoperatively. Symptoms include chest pain, persistent dysphagia in 5%, gas bloat in 2% to 4%, diarrhea in up to 20%, and dumping syndrome in up to 30%. Symptoms are often nonspecific, arising from recurrent or persistent GERD, anatomic complications such as disrupted or herniated wrap, functional disturbances such as rapid gastric emptying or altered gastric accommodation, or alternative diagnoses such as cyclic vomiting syndrome or food allergy. Detailed investigation, including various combinations of pHmetry, videofluoroscopy, endoscopy, motility studies, and dumping provocation testing, may be required to clarify pathophysiology and guide management.
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