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Updated: Aug 17, 2026

Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains
Published on: June 8, 2018
Primate adult brain cell autotransplantation, a new tool for brain repair?
Jean-François Brunet1, Eric Rouiller, Thierry Wannier
1Department of Neurosurgery, Lausanne University Hospital, Bugnon 46, 1011 Lausanne, Switzerland. Jean-Francois.Brunet@chuv.hospvd.ch
Abstract:
If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications.

