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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

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Paradoxical embolism with a patent foramen ovale and atrial septal aneurysm

D J Beacock1, V B Watt, G D Oakley

  • 1Department of Cardiology, Chesterman Wing, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK.

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
|May 26, 2005
PubMed

Insights

Patent foramen ovale (PFO) and atrial septal aneurysm are potential risks for cryptogenic stroke. These cases illustrate paradoxical embolization as a cerebrovascular accident mechanism, discussing PFO diagnosis and literature.

Area of Science:

  • Cardiology
  • Neurology
  • Vascular Medicine

Background:

  • Cryptogenic stroke is a significant clinical challenge.
  • Patent foramen ovale (PFO) and atrial septal aneurysm are implicated as risk factors.
  • Understanding the mechanisms of stroke is crucial for prevention.

Observation:

  • Two distinct cases of cryptogenic stroke are presented.
  • These cases provide direct illustration of paradoxical embolization.
  • The role of PFO in paradoxical embolization is highlighted.

Findings:

  • Paradoxical embolization via PFO is demonstrated as a mechanism for cerebrovascular accidents.
  • Diagnostic approaches for PFO are discussed.
  • The findings support the link between specific cardiac anomalies and stroke.

Implications:

  • Improved diagnostic strategies for PFO may aid in stroke risk stratification.
  • Understanding paradoxical embolization can lead to targeted therapeutic interventions.
  • Further research into cardiac-neurologic connections is warranted.

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