Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Lead and blood pressure].

P Apostoli1, A Corulli, P Carta

  • 1Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Università degli Studi di Brescia, Italy. apostoli@med.unibs.it

Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia
|May 27, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diabetes and work: The need of a close collaboration between diabetologist and occupational physician.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2019
Same author

Exposure to individual and multiple carcinogenic metals during paediatric age: an experience from an Italian urban scenario.

Annali di igiene : medicina preventiva e di comunita·2017
Same author

Urinary biomarkers of exposure and of oxidative damage in children exposed to low airborne concentrations of benzene.

Environmental research·2015
Same author

Exhaled breath analysis in suspected cases of non-small-cell lung cancer: a cross-sectional study.

Journal of breath research·2015
Same author

Impact of intraoperative hypotension and blood pressure fluctuations on early postoperative delirium after non-cardiac surgery.

British journal of anaesthesia·2015
Same author

Porphyrin conjugated SiC/SiOx nanowires for X-ray-excited photodynamic therapy.

Scientific reports·2015

Lead exposure is linked to increased blood pressure in both occupationally exposed individuals and the general population. This study confirms a modest but significant correlation, particularly evident at lower lead levels.

Area of Science:

  • Environmental Health
  • Cardiovascular Science
  • Toxicology

Context:

  • Hypertension is a major cardiovascular risk factor.
  • Previous studies suggest a link between lead (Pb) exposure and elevated blood pressure.
  • Concerns exist regarding potential increases in morbidity and mortality due to lead-induced hypertension.

Purpose:

  • To investigate the relationship between blood lead levels and blood pressure.
  • To compare this relationship in occupationally exposed individuals and the general population.

Summary:

  • A statistically significant positive correlation was found between blood lead levels and both systolic and diastolic blood pressure in 303 occupationally exposed subjects (blood-Pb 10-80 microg/dl) and 206 general population subjects (blood-Pb 0.5-9 microg/dl).

Related Experiment Videos

  • The effect of lead on blood pressure was proportionally higher in hypertensive subjects from the non-occupationally exposed group.
  • Lead's effect on blood pressure is observed across a wide dose range, is quantitatively modest, and appears more pronounced at lower doses, suggesting potential dose-dependent mechanisms.

    • Impact:

    • Confirms the causal link between lead exposure and elevated blood pressure.
    • Highlights the public health significance of even low-level lead exposure.
    • Suggests the need for further research into the mechanisms of lead's cardiovascular effects at different exposure levels.