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Trace elements and the electroencephalogram during long-term lithium treatment
N S Harvey1, J Jarratt, N I Ward
1University of Sheffield, Royal Hallamshire Hospital.
Abstract:
Endogenous bromine has been found to be raised during lithium treatment, and it has been suggested that it may augment the therapeutic effect of lithium. Our findings in a study of 12 patients and 12 controls support this contention. Electroencephalographic effects of bromine, vanadium and aluminium were studied--higher bromine and vanadium levels were associated with irregular cortical activity. Electroencephalographic abnormalities were associated with more side-effects of lithium.