Salmonella meningitis and antimicrobial susceptibilities

Somporn Srifuengfung1, Kulkanya Chokephaibulkit, Thitiya Yungyuen

  • 1Department of Microbiology, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Insights

Salmonella meningitis is a significant concern in developing nations, particularly affecting infants. Understanding Salmonella serogroups and antimicrobial resistance is crucial for effective treatment strategies.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Pediatrics

Background:

  • Meningitis caused by Salmonella species is a notable issue in developing countries.
  • Early diagnosis and treatment are critical for managing bacterial meningitis.

Purpose of the Study:

  • To analyze the characteristics of Salmonella meningitis cases.
  • To determine the predominant Salmonella serogroups involved.
  • To investigate antimicrobial susceptibility patterns for treatment guidance.

Main Methods:

  • Retrospective study of patients with suspected bacterial meningitis admitted to Siriraj Hospital from 1986 to 2001.
  • Identification and serogrouping of Salmonella isolates.
  • Antimicrobial susceptibility testing of Salmonella meningitis isolates.

Main Results:

  • Nineteen cases of Salmonella meningitis were identified.
  • Salmonella serogroup D was the most prevalent, followed by serogroups C, B, and H.
  • The majority of affected patients were children under one year of age.

Conclusions:

  • Salmonella meningitis predominantly affects infants.
  • Serogroup D is the most common cause of Salmonella meningitis in this cohort.
  • Antimicrobial susceptibility data are essential for guiding treatment decisions in Salmonella meningitis.

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