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Salmonella meningitis and antimicrobial susceptibilities
Somporn Srifuengfung1, Kulkanya Chokephaibulkit, Thitiya Yungyuen
1Department of Microbiology, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Summary
Salmonella meningitis is a significant concern in developing nations, particularly affecting infants. Understanding Salmonella serogroups and antimicrobial resistance is crucial for effective treatment strategies.
Area of Science:
- Infectious Diseases
- Microbiology
- Pediatrics
Background:
- Meningitis caused by Salmonella species is a notable issue in developing countries.
- Early diagnosis and treatment are critical for managing bacterial meningitis.
Purpose of the Study:
- To analyze the characteristics of Salmonella meningitis cases.
- To determine the predominant Salmonella serogroups involved.
- To investigate antimicrobial susceptibility patterns for treatment guidance.
Main Methods:
- Retrospective study of patients with suspected bacterial meningitis admitted to Siriraj Hospital from 1986 to 2001.
- Identification and serogrouping of Salmonella isolates.
- Antimicrobial susceptibility testing of Salmonella meningitis isolates.
Main Results:
- Nineteen cases of Salmonella meningitis were identified.
- Salmonella serogroup D was the most prevalent, followed by serogroups C, B, and H.
- The majority of affected patients were children under one year of age.
Conclusions:
- Salmonella meningitis predominantly affects infants.
- Serogroup D is the most common cause of Salmonella meningitis in this cohort.
- Antimicrobial susceptibility data are essential for guiding treatment decisions in Salmonella meningitis.