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The UK Human Genome Mapping Project online computing service.

F R Rysavy1, M J Bishop, G P Gibbs

  • 1MRC Clinical Research Centre, Harrow, Middlesex, UK.

Computer Applications in the Biosciences : CABIOS
|April 1, 1992
PubMed
Summary
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The Medical Research Council developed advanced computing and networking facilities to support the UK Human Genome Mapping Project (HGMP). This system connects genetics research centers, offering essential online computational services.

Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • The Human Genome Mapping Project (HGMP) requires robust computational infrastructure.
  • Distributed genetics research necessitates integrated computing and networking solutions.

Purpose of the Study:

  • To present the computing and networking facilities developed by the Medical Research Council (MRC) for the UK HGMP.
  • To describe the design and implementation of the MRC's online computing support system.

Main Methods:

  • Development of a 'client/server' network architecture.
  • Integration of diverse hardware including Sun, IBM, DEC, and Apple systems.
  • Connection to national and international wide-area networks and high-speed links.

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Main Results:

  • Established a connected network of computing facilities across UK genetics and molecular biology centers.
  • Implemented a functional client/server system providing online computational services.
  • Facilitated access to computing resources for the UK human genetics research community.

Conclusions:

  • The MRC's developed system effectively supports the computational needs of the UK HGMP.
  • The implemented network enhances collaboration and data sharing among genetics researchers.
  • Further information on services is available directly from the UK HGMP Resource Centre (HGMP-RC).