Related Experiment Videos
Aneurysmal bone cyst. A clinicopathologic study of 238 cases
A M Vergel De Dios1, J R Bond, T C Shives
1Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota 55905.
Cancer
|June 15, 1992
Summary
Aneurysmal bone cysts (ABC) are rare, nonneoplastic bone lesions primarily affecting young individuals. Recurrence after curettage affects 19% of patients, most commonly within two years post-surgery.
Area of Science:
- Orthopedic Oncology
- Pathology
Background:
- Aneurysmal bone cyst (ABC) is a rare, nonneoplastic, expansile bone lesion.
- It predominantly affects children and young adults, with primary ABC being less common than giant cell tumors of bone.
Purpose of the Study:
- To characterize the clinical, radiographic, and histopathologic features of aneurysmal bone cysts.
- To evaluate recurrence rates following treatment for ABC.
Main Methods:
- Retrospective review of 238 patients with ABC diagnosed and treated at the Mayo Clinic.
- Analysis of radiographic findings (including CT and MRI) and histopathologic features of typical and solid variant ABC.
- Evaluation of treatment outcomes, specifically recurrence rates after curettage, in 153 patients.
Main Results:
- Over 80% of ABC lesions were located in long bones, flat bones, or the spinal column.
- 95% of treated lesions were typical ABC, with the remaining 5% being solid variants; minimal histologic differences were noted between variants.
- Radiographically, ABC presents as an eccentric, expansile lesion, often in the metaphysis of long bones.
- Recurrence after curettage occurred in 19% of patients, with most recurrences observed within the first two postoperative years.
Conclusions:
- Aneurysmal bone cysts exhibit characteristic radiographic features and can occur in various skeletal locations.
- While solid variants exist, they share histologic similarities with typical ABC.
- Curettage has a significant recurrence rate, highlighting the need for careful monitoring post-treatment.