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Updated: Aug 17, 2026

Quantification of Orofacial Phenotypes in Xenopus
09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

Orofacial clefting: recent insights into a complex trait

Astanand Jugessur1, Jeffrey C Murray

  • 1Department of Paediatrics, University of Iowa, Iowa City, IA 52242, USA.

Current Opinion in Genetics & Development
|May 27, 2005
PubMed

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X-linked Traits01:19

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Pleiotropy

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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
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