Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Research progress on Helicobacter pylori outer membrane protein.

Shi-He Shao1, Hua Wang, Shun-Gen Chai

  • 1Department of Medical Microbiology and Parasitology, Medical Technology College, Jiangsu University, Zhenjiang 212001, Jiangsu Province, China. ljxwl123@163.com

World Journal of Gastroenterology
|May 27, 2005
PubMed
Summary

Helicobacter pylori outer membrane proteins (OMPs) are key to its pathogenicity. Research highlights their role in diagnosis, immunity, and severe gastric mucosa damage linked to high bacterial density.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phosphine-free synthesis of high quality ZnSe, ZnSe/ZnS, and Cu-, Mn-doped ZnSe nanocrystals.

Dalton transactions (Cambridge, England : 2003)·2009
Same author

Comparative study of three PCR-based copy number variant approaches, CFMSA, M-PCR, and MLPA, in 22q11.2 deletion syndrome.

Genetic testing and molecular biomarkers·2009
Same author

[Influence on electroacupuncture at "Qiangzhuang" acupoints for neuro-immune regulation of sub-acute aged rats].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion·2009
Same author

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2009
Same author

[Treatment of nonunion of tibia with superficial peroneal vascular fascia pedicel tibiofibular periosteal flap].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2009
Same author

[Expression, purification and activity analysis of BCG HSP70.].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology·2009

Area of Science:

  • Microbiology
  • Immunology
  • Gastroenterology

Background:

  • Helicobacter pylori (H pylori) is a common human pathogen colonizing the gastric mucosa.
  • H pylori possesses 95 paralogous gene families, including a significant outer membrane protein (OMP) family with 32 members.

Purpose of the Study:

  • To review research progress on the pathogenicity of H pylori outer membrane proteins (OMPs).
  • To elucidate the role of H pylori OMPs in disease development and host response.

Main Methods:

  • Literature review of studies focusing on H pylori OMPs.
  • Analysis of the association between OMPs and H pylori infection outcomes.

Main Results:

  • H pylori OMPs are crucial for bacterial diagnosis, immune response, and pathogenicity.

Related Experiment Videos

  • These OMPs are significantly linked to high H pylori density, gastric mucosa damage, elevated IL-8 levels, and neutrophil infiltration.

    • Conclusions:

    • H pylori OMPs play a critical role in the pathogenesis of H pylori infections.
    • Understanding OMP function is vital for developing diagnostic and therapeutic strategies against H pylori.