Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurotransmitters in carotid body development.

Aida Bairam1, John L Carroll

  • 1Unité de recherche en périnatologie, Centre Hospitalier Universitaire de Québec, Hôpital Saint-François d'Assise, Université Laval, Québec, Centre de Recherche, D0-717, 10, rue de l'Espinay, Que. (PQ), Canada G1L 3L5. aida.bairam@crsfa.ulaval.ca

Respiratory Physiology & Neurobiology
|May 28, 2005
PubMed
Summary

Neurotransmitters like dopamine and acetylcholine in the carotid body influence chemosensory signaling during development. Their precise role in maturing oxygen sensing in newborn carotid chemoreceptors remains unclear.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026
Same author

A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2024
Same author

Corrigendum: Highly comparative time series analysis of oxygen saturation and heart rate to predict respiratory outcomes in extremely preterm infants (2024<i>Physiol. Meas.</i> 45 055025).

Physiological measurement·2024
Same author

Commercial infant products influence body position and muscle use.

Early human development·2024
Same author

Highly comparative time series analysis of oxygen saturation and heart rate to predict respiratory outcomes in extremely preterm infants.

Physiological measurement·2024
Same author

Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Infants Born Extremely Preterm.

The Journal of pediatrics·2024

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Physiology

Background:

  • The carotid body is a crucial chemoreceptor organ sensing blood oxygen levels.
  • Neurotransmitters play a role in carotid body function, but their developmental impact is not fully understood.

Purpose of the Study:

  • To review the role of neurotransmitters in carotid body chemosensory activity during postnatal development.
  • To investigate the involvement of dopamine, acetylcholine, adenosine, and neuropeptides in chemoreceptor maturation.

Main Methods:

  • Literature review of existing studies on carotid body neurotransmitters and postnatal development.
  • Analysis of evidence for neurotransmitter involvement in signal transmission and chemosensory maturation.

Main Results:

Related Experiment Videos

  • Neurotransmitters are involved in signal transmission from carotid body cells to the sinus nerve.
  • Some aspects of this neurotransmitter involvement show age- or maturation-dependence.

Conclusions:

  • While neurotransmitters are present and active early, their direct role in the maturation of oxygen sensing by carotid chemoreceptors postnatally requires further investigation.
  • The precise contribution of prenatally expressed neurotransmitters to postnatal functional maturation is unresolved.