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Nicorandil induced oral ulceration
1Department of Maxillofacial Surgery, University Hospital Birmingham Foundation Trust, Edgbaston, Birmingham B15 2TH, UK. k.webster@bham.ac.uk
British Dental Journal
|May 28, 2005
Summary
Nicorandil medication is linked to oral ulceration. This case series highlights the association for dental professionals, adding to existing reports.
Area of Science:
- Oral medicine
- Pharmacology
- Dental research
Background:
- Oral ulceration presents with diverse etiologies.
- A potential link between Nicorandil and oral ulceration has been previously reported.
- Existing literature lacks comprehensive reporting in general dental practice publications.
Observation:
- A case series of seven patients experiencing oral ulceration was investigated.
- Clinical presentations and patient histories were documented.
- The observed cases were compared against existing literature data.
Findings:
- The study confirms a recurring association between Nicorandil use and the development of oral ulceration.
- The findings align with previous case reports, reinforcing the drug's potential role.
- This series provides further evidence for Nicorandil-induced oral ulceration.
Implications:
- This research underscores the importance of considering Nicorandil as a potential cause of oral ulceration in clinical dental practice.
- Dentists should be aware of this adverse drug effect for accurate diagnosis and patient management.
- Further investigation into the mechanism of Nicorandil-induced oral ulceration is warranted.