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[Effect of femoral vein-occlusion on replanted limb survival at different stages]
Feng Yuan1, Guangrong Yu, Xuansong Cai
1Department of Orthopedics, Tongji Hospital Affiliated to Tongji University, Shanghai, 200065, PR China.
Objective:
To study the effect of vein-occlusion on the replanted limb survival in SD rats at different stages.
Methods:
Twenty-five adult SD rats were randomly divided into 5 groups according to the time of the femoral vein occlusion after the replanted limbs: 2-, 3-, 4-, 6-, and 8-day groups. The limbs were observed through naked eye, measurement of dermal temperature and angiography.
Results:
No formation of collateral veinlet was found, and necrosis was seen in the replanted limbs of 2-, 3-day groups. Reflux-vein was gradually increased in the replanted limbs of 4, 6, and 8 day groups. Angiographic score of capillary density and dermal temperature in the thigh muscles were greater in groups 4-, 6-, and 8-day than in groups 2- and 3-day.
Conclusion:
Within 2 and 3 days,the replanted limbs of SD rats will necrose because of vein-occlusion; and 4 days later the replanted limbs can survive depending on the reflux-vein of new collateral veinlet.
