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[Role of pre-coating in artificial vessel endothelialization]
1Vascular Surgery, the First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, 400016, PR China. xiaolittlehappy@yahoo.com
Objective:
To understand the value of pre-coating in artificial vessel endothelialization.
Methods:
Literature concerning pre-coating in artificial vessel endothelialization was extensively reviewed.
Results:
Pre-coating included chemical coatings (collagen, fibronectin, laminin, poly-l-lysin, gelatin and extracellular matrix), pre-clotting (plasma, blood, serum and fibrin glue), chemical bonding (heparin, RGD and lectins) and surface modification. Most of them could enhance the adhesion of the endothelial cells.
Conclusion:
Pre-coating could improve endothelialization, but further research is needed to search for the appropriate concentration and incubation time.
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