Related Experiment Video
Updated: Aug 18, 2026

Detection of Signaling Effector-Complexes Downstream of BMP4 Using in situ PLA, a Proximity Ligation Assay
Published on: March 3, 2011
[Mini review on inhibins and activins]
1Gunma University.
Abstract:
Recent researches on inhibin and activin were reviewed. This mini review contains brief history of researches on inhibins and activins, criteria, chemistry, the site of production of these two hormones, assay method (bio- and radioimmunoassay), changes of serum inhibin levels in normal physiologic states and in various pathologic states of men and women, actions of inhibins and activins upon FSH and LH secretion from the pituitary, upon other pituitary functions, upon brain functions, erythropoiesis, erythroleukemia, bone and bone marrow, immunology, other organs such as liver, pancreas, adrenals, placenta, Xenopus oocyte and general cell proliferation, paracrine and autocrine actions of these hormones inside the ovary and the testis, activin receptor, inhibin receptor, follistatin, effects of exogenous administration of recombinant inhibin and activin, and TGF-beta super gene family.
Related Concept Videos
Feedback Inhibition
Intracellular Hormone Receptors
Structural Protein Function
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to form...
Eukaryotic Transcription Inhibitors
Eukaryotic transcription inhibitors usually contain two distinct domains, a DNA...
Introduction to Actin
Activation of Integrins
In "outside-in signaling," external factors in the extracellular space bind to exposed ligand binding sites on integrins. This causes the inactive protein to undergo a conformational change to become active. Integrins are often clustered on the cell membrane. Repetitive and regularly spaced ligand binding events provide an effective stimulus.

