[Nerium oleander self poisoning treated with digoxin-specific antibodies]
B Bourgeois1, P Incagnoli, J Hanna
1Samu de Grenoble, CHU de Grenoble, BP 207, 38043 Grenoble, France. BBourgeois@chu-grenoble.fr
Abstract:
A chronically depressed 44-year-old man was rescued by the French medicalised ambulance service four hours after the ingestion of Nerium oleander leaves in a suicide attempt. Cardiotoxicity was evidenced by the presence of bradycardia with mental confusion and vomiting. The patient was empirically treated in the prehospital phase with a single dose of digoxin-specific Fab antibody fragments (Digidot). In spite of this treatment, the patient presented a new episode of important bradycardia (25 b/minute). Thereafter, the patient's rhythm stabilized and neurological signs and vomiting resolved. The patient recovered uneventfully and was discharged from the intensive care unit two days later.
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