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Non-right handedness among ELBW and term children at eight years in relation to cognitive function and school

S Saigal1, P Rosenbaum, P Szatmari

  • 1Department of Pediatrics, McMaster University, Hamilton, Ontario.

Insights

Extremely low-birthweight (ELBW) children show higher non-right handedness, linked to neurological issues. However, non-right handedness in ELBW children did not correlate with cognitive or school performance deficits.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Pediatrics

Background:

  • Non-right handedness is associated with various neurodevelopmental conditions.
  • Extremely low-birthweight (ELBW) infants face higher risks for neurological and developmental challenges.
  • Understanding the link between birth weight, handedness, and neurodevelopment is crucial for early intervention.

Purpose of the Study:

  • To investigate the relationship between handedness and neurodevelopmental outcomes in extremely low-birthweight (ELBW) children.
  • To examine associations between non-right handedness, neurological deficits, cognitive function, and school performance in ELBW children compared to term controls.
  • To test the hypothesis that early brain insults in ELBW children lead to subtle cognitive deficits and school difficulties in non-right handed individuals.

Main Methods:

  • A cohort study comparing 114 extremely low-birthweight (ELBW) children with 145 term-born controls at eight years of age.
  • Assessment of handedness (right, left, mixed) and neurological status.
  • Evaluation of cognitive function, school performance, and prevalence of learning difficulties using standardized tests.

Main Results:

  • The prevalence of non-right handedness was significantly higher in ELBW children (31%) compared to term controls (19%).
  • ELBW children with diagnosed neurological impairments were significantly more likely to exhibit non-right handedness.
  • No significant differences were found in cognitive function, school performance, or learning difficulties between right-handed and non-right handed ELBW children or controls.

Conclusions:

  • Neurological impairment in ELBW children is associated with a higher prevalence of non-right handedness.
  • The study does not support the hypothesis that early brain injury in ELBW children leads to subtle cognitive deficits or poorer school performance specifically in non-right handed individuals.
  • Handedness alone, without other neurological deficits, may not be a reliable indicator of cognitive or academic challenges in ELBW survivors.

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