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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
Identification of antitumor activity of pyrazole oxime ethers
Hyun-Ja Park1, Kyung Lee, Su-Jin Park
1Bio-Organic Science Division, Korea Research Institute of Chemical Technology, PO Box 107, Yusong, Taejon 305-600, Republic of Korea.
Bioorganic & Medicinal Chemistry Letters
|June 1, 2005
Abstract:
A series of pyrazole oxime ether derivatives were prepared and examined as cytotoxic agents. In particular, 5-phenoxypyrazole was comparable to doxorubicin, while exhibiting very potent cytotoxicity against XF 498 and HCT15.
